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This thesis focused on the synthesised ATRA retinoid analogues, EC 19 and EC23 and aimed to evaluate their biological activity in relation to ATRA on a number of different embryonic and adult model systems. Unlike ATRA, these compounds do not isomerise in response to light or heat. Data show that both compounds are effective at inducing differentiation.

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But really we give the man too much credit. Without the Chinese stock market sell off on Tuesday, without the unexpectedly large decline in durable goods orders, without the ongoing turmoil in the subprime lending market, without the recent rise in crude oil prices, without the geopolitical worries in Iraq and Iran and Afghanistan, would Greenspan’s declaration have moved the markets? Isn’t it just as feasible that his mild pessimism touched a chord with what many traders were already feeling? Enough with the Great Man Greenspan theory of economic history. Declared that it had been triggered by a massive sell off in the Shanghai market.

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